Transcribing β-cell mitochondria in health and disease
نویسندگان
چکیده
منابع مشابه
Transcribing β-cell mitochondria in health and disease
BACKGROUND The recent genome-wide association studies (GWAS) of Type 2 Diabetes (T2D) have identified the pancreatic β-cell as the culprit in the pathogenesis of the disease. Mitochondrial metabolism plays a crucial role in the processes controlling release of insulin and β-cell mass. This notion implies that mechanisms controlling mitochondrial function have the potential to play a decisive pa...
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1 Department of Sport Biology, Research Centre in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Rua Dr. Plácido Costa 91, 4200-450 Porto, Portugal 2 Sezione di Fisiologia, Dipartimento delle Scienze Biologiche, Università degli Studi di Napoli “Federico II”, Via Mezzocannone 8, 80134 Napoli, Italy 3 Department of Applied Physiology and Kinesiology, Colle...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2017
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2017.05.014